mujast MUJAST Mountain Top University Journal of Applied Sciences and Technology MUJAST 2736-2310 Mountain Top University Prayer City, Ogun State, Nigeria LEGACY-di0o1 10.mtu/legacy-di0o1 Research Article Hypolipidemic effect of aqueous and ethanol extracts of Alafia barteri (leaf and root) in formaldehyde-induced arthritis in male mice Kolawole Kolawole Mountain Top University, Nigeria O.* I. Mountain Top University, Nigeria Ebuehi Ebuehi Mountain Top University, Nigeria T. O. A. Mountain Top University, Nigeria Lawal Lawal Mountain Top University, Nigeria A. R. Mountain Top University, Nigeria Amize Amize Mountain Top University, Nigeria Alabi E. C. and Mountain Top University, Nigeria S. T. Mountain Top University, Nigeria 04 10 2023 3 1 © 2023 Mountain Top University. Licensed under Creative Commons Attribution 4.0 International (CC-BY 4.0). 2023 Mountain Top University https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

<p class="ql-align-justify"><em>Alafia barteri&nbsp;</em>is valued for its effectiveness in the traditional medicine system in Nigeria and other African countries. This study aims at evaluating the hypolipidemic effect of the aqueous and ethanol leaf and root extracts of&nbsp;<em>Alafia barteri</em>&nbsp;in formaldehyde-induced arthritic mice. 77 healthy Swiss albino male mice (30-35 g) were randomized into eleven groups of five mice each and extracts were administered for 10 days at 200 mg/kg and 400 mg/kg. Arthritis was induced by sub-plantar injection of 0.1 mL of 2 % formaldehyde. Serum lipid profile was evaluated after blood sample collection. Results of this study revealed that the&nbsp;aqueous and ethanol leaf extracts<em>&nbsp;</em>caused significant reduction(p˂0.05)&nbsp;in triglyceride and total cholesterol levels, but increased&nbsp;HDL-cholesterol levels&nbsp;compared to the arthritic control&nbsp;which is suggestive of their hypo-lipidemic effects in arthritic mice.&nbsp;</p><p class="ql-align-justify"><br></p><p class="ql-align-justify"><br></p>

 <p class="ql-align-justify"><em>Alafia barteri, A</em>rthritic, Sub-plantar, Hypolipidemic</p><p><br></p> Introduction & Full Text Notice

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